The reference site for Cefuroxime

Cefuroxime is an enteral second-generation cephalosporin antibiotic. It was discovered by Glaxo, now GlaxoSmithKline and first marketed in 1978 as Zinacef.

WHAT IS Cefuroxime?

Cefuroxime is an antibiotic in a class of drugs called cephalosporins. This medicine fights bacteria in the body.

Cefuroxime is used to treat many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.


Brand Name(s): Ceftin; Zinacef
CAS nº: 55268-75-2
(sef yur ox eem)


Product Info

The sections below will provide you with more specific information and guidelines related to cefuroxime and its correct use. Please read them carefully.

FDA Information

Cefuroxime was approved by the US FDA in December 1987. A prescription is required for this medicine.

Please visit the official site of the FDA for further information.

Why is this medication prescribed?

Cefuroxime is a semisynthetic cephalosporin antibiotic, chemically similar to penicillin. It works by stopping the growth of bacteria.

Cefuroxime is effective against susceptible bacterias causing infections of the middle ear, tonsillitis, throat infections, laryngitis, bronchitis, and pneumonia. It is also used in treating urinary tract infections, skin infections, and gonorrhea.

Additionally, it is useful in treating acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD).

Note: cefuroxime will not work for colds, flu, or other viral infections.

Other uses for this medicine

This medication has not been approved for any alternative uses other than those mentioned in the product information section.

Dosage and using this medicine

Cefuroxime comes as a tablet and a suspension (liquid) to be taken orally. It is usually taken every 12 hours (twice a day) for 7-10 days.

Take this medication exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. This medicine can be taken on an empty stomach or with food or milk if it causes stomach upset.

To ensure that you get the correct dose, measure the liquid form of cefuroxime with a dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Shake the suspension well before measuring a dose.

Take this medicine at evenly spaced intervals to keep a constant level of drug in the body. It is important to take cefuroxime regularly to get the most benefit.

Take all of the cefuroxime that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.

What special precautions should I follow?


Please tell your doctor if you have kidney disease, a gastrointestinal (digestive) disease such as colitis, or have an inherited protein metabolism disorder called phenylketonuria. You may not be able to take cefuroxime, or you may require a dosage adjustment or special monitoring during treatment if you have either of the conditions listed above.

Do not take cefuroxime at the same time as antacids (e.g., Tums®, Maalox®, Rolaids®, others) or other medications taken to reduce stomach acid such as cimetidine (Tagamet®, Tagamet HB®, others), famotidine (Pepcid®, Pepcid AC®, Pepcid RPD®, others), ranitidine (Zantac®, others), or nizatidine (Axid®, others) unless otherwise directed by your doctor. Antacids and stomach acid reducers may reduce the effects of cefuroxime.

Certain brands of cefuroxime suspension and cefuroxime suspension sachets have aspartame (a source of phenylalanine) in them and should not be used by anyone with the inherited protein metabolism disorder called phenylketonuria. Talk to your doctor if you have phenylketonuria or have a family history of phenylketonuria.

Furthermore, do not take this medicine if you have ever had an allergic reaction to another cephalosporin or to a penicillin unless your doctor is aware of the allergy and monitors your therapy.

The cefuroxime (Ceftin®) suspension contains sucrose. Individuals with diabetes may need to be aware of the sucrose contained in this suspension.

Additionally, cefuroxime is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not, however, take cefuroxime without first talking to your doctor if you are pregnant or could become pregnant during treatment.

So too, this medicine passes into breast milk and may affect a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

What should I do if I forget a dose?

Take the missed dose as soon as you remember, then try to evenly space the rest of the doses for that day until you can return to a normal schedule.

Do not take a double dose of this medication unless otherwise directed by your doctor.

What side effects can this medication cause?

If you experience any of the following serious side effects, stop taking cefuroxime and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, face, or tongue, hives, or a rash)
rash, redness, or itching
severe nausea
vomiting or diarrhea
mucous or blood in the stool
unusual bleeding or bruising

Other, less serious side effects may also occur. Continue to take the medication and talk to your doctor if you experience

mild nausea
yeast infection of the mouth or vagina

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Store the tablets at room temperature away from moisture and heat. The suspension can be stored at room temperature or in the refrigerator. Do not freeze.

Remember to throw away any unused medication after 10 days and, if necessary, talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In the case of an overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, please call the local emergency services on 911.

Symptoms of overdose may include:

abdominal cramps

Product Images


Below you will find images and specific information on the principal types of cefuroxime that exist, including their respective brand name(s), strength, inscription codes, manufacturers and/or distributors.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Strength(s): 1.5 MG/50 ML
Imprint: ZINACEF

Strength(s): 250 MG
Imprint: APO | C 250
Manufacturer: APOTEX CORP.

Strength(s): 250 MG
Imprint: RX 751
Manufacturer: RANBAXY

Strength(s): 500 MG
Imprint: APO | C 500
Manufacturer: APOTEX CORP.

Strength(s): 500 MG
Imprint: GX EG2

Strength(s): 500 MG
Imprint: RX 752
Manufacturer: RANBAXY

Strength(s): 750 MG/50 ML
Imprint: ZINACEF

Strength(s): 1.5 G
Imprint: ZINACEF

Strength(s): 7.5 G
Imprint: ZINACEF

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